Questions on Calibration

Do I need a maturity calibration for every concrete mix design?
Yes. A calibration is only valid for each unique concrete mix, as the strength development changes depending on the mix design.
Do I need a new maturity calibration if I change one of my suppliers
It depends. You should at least validate your maturity calibration as described above. If the difference is more than 10%, you should perform a recalibration.
Do I need a new maturity calibration if I add admixtures?
Most likely. Many admixtures change the properties and strength development of your concrete mix and you must ensure that your maturity calibration is accurate.